Endocrine Abstracts

Type 2 diabetes (T2DM) patients are at high risk for vascular complications. Some of them have even a higher risk during metformin therapy, as we have recently shown by associations of polymorphisms in the Oct1 gene with a therapy-dependent increased risk of cardiovascular death. In this study, we investigated whether Oct1 gene variants were associated with cardiovascular characteristics such as pulse wave velocity (PWV), echocardiographic parameters and intima/media thickness...